AssociationofSleepDurationandQualityWithSubclinicalAtherosclerosisJACCResearchArticleJan22,:73(2),10./j.jacc..10.本文由“天纳”临床学术信息人工智能系统自动翻译CentralIllustrationBackgroundSleepdurationandqualityhavebeenassociatedwithincreasedcardiovascularrisk.However,largestudieslinkingobjectivelymeasuredsleepandsubclinicalatherosclerosisassessedinmultiplevascularsitesarelacking.睡眠时间和质量与心血管风险增加有关。然而，目前缺乏在多个血管部位客观测量睡眠与亚临床动脉粥样硬化之间联系的大型研究。ObjectivesThepurposeofthisstudywastoevaluatetheassociationofactigraphy-measuredsleepparameterswithsubclinicalatherosclerosisinanasymptomaticmiddle-agedpopulation,andinvestigateinteractionsamongsleep,conventionalriskfactors,psychosocialfactors,dietaryhabits,andinflammation.本研究的目的是评估在无症状的中年人群中活动测量的睡眠参数与亚临床动脉粥样硬化的关系，并研究睡眠、传统危险因素、心理社会因素、饮食习惯和炎症之间的相互作用。MethodsSeven-dayactigraphicrecordingwasperformedin3,participants(age45.8±4.3years;62.6%men)fromthePESA(ProgressionofEarlySubclinicalAtherosclerosis)study.Fourgroupsweredefined:veryshortsleepduration6h,shortsleepduration6to7h,referencesleepduration7to8h,andlongsleepduration8h.Sleepfragmentationindexwasdefinedasthesumofthemovementindexandfragmentationindex.Carotidandfemoral3-dimensionalvascularultrasoundandcardiac
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